ABSTRACT: INTRODUCTION: |
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In 1944 an Italian chemist, C. J. Cavallito, with his colleague J H Bailey 1 first isolated an unstable, odourous sulphur containing compound from extracts of fresh garlic and demonstrated its antibacterial properties. The substance was named allicin, after the generic name for the plant Allium Sativum. Researchers Stoll and Seebeck, also working with garlic, discovered an odourless sulphur-containing compound called alliin which they fully characterised some years later. 2 This they found to be converted by a second garlic constituent, an enzyme called allinase, to form allicin. The researchers made an additional remarkable discovery: When they studied cloves in cross section they found that alliin and allinase are stored in different compartments. In an undamaged clove they remain completely separate, but once its structure is ruptured - typically by cutting - the two substances come into contact and form allicin.
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European Journal for Nutraceutical Research